Synthesis, characterization and biological activity evaluation of Ni(II) and Cu(II) complexes of a Schiff base derived from S-benzyldithiocarbazate (SBDTC) and cinnamaldehyde

Abstract

Bidentate NS donor ligand was prepared from the condensation reaction of cinnamaldehyde with S-benzyldithiocarbazate (SBDTC). Reaction of the Schiff base ligand with the metal ions Ni (II) and Cu (II) afforded complexes with the general formula [M(II)(NS)2]. Molecular structures of the Schiff base ligand and its complexes were established through elemental analysis, conductivity and magnetic susceptibility measurements as well as spectroscopic data (FT-IR, UV-Vis and ESI-MS). The geometrical structures of the metal complexes are square planar. The biological activities of the ligand and its complexes were investigated against the gram-positive and gram-negative bacteria and the fungus strain. The metal complexes were shown to possess more bioactivity than the uncomplexed ligand.