Investigation of simple and accurate method for synthesis of 2, 4, 5-triary-1h-imidazole derivatives using SIO2-NAHSO4 under solvent-free condition

Abstract

This paper presents a mixture of benzyl, aromatic aldehyde and ammonium acetate in presence of SiO2-NaHSO4 under solvent-free condition were converted to 2, 4, 5-Triaryl-1H-Imidazoles. The short reaction time, cleaner reaction, and easy workup make this protocol practical and economically attractive. We have had the option to present a proficient and earth inviting for the union of imidazole subsidiaries by means of buildup of benzil with different sweet-smelling aldehydes and ammonium acetic acid derivation. Subsequently, revealed SiO2-NaHSO4 as impetus which could give an effective, modest, simple partition, high return and basic course under dissolvable free condition for the union of imidazoles.