Isolation of pathogens from urinary tract infection in HIV patient and effect of turmeric extract as an anti-bacterial agent on it

Abstract

HIV and Opportunistic infection are the two words which go parallel. HIV patients are immune-suppressed patients, so they are prone to many opportunistic infections like Tuberculosis, Meningococcal infections, Parasitic & Bacterial infections of stool, etc. Urinary Tract Infection is an important opportunistic infections amongst the HIV patients. Study include infection prevalence and cause of infection. To rule out Urinary Tract Infection, urine culture along with antibiotic sensitivity are important investigations. In selected HIV positive patients, we carried out urine culture and isolated organism in pure culture. Identification and antibiotic sensitivity test is performed by manual method. Total 115 specimens were tested and noted the following result; 55 (47.82%) of them shown bacterial growth while 58 (50.43%) no bacterial Growth while 2 (1.74%) are yeast. Organisms isolated are: E. coli in twelve cases (21.81 %) Pseudomonas sp. in five cases (9.09%), Enterococcus sp. in sixteen cases (29.09%) Staphylococcus sp. in six cases (10.90%) Klebsiella sp. twelve (21.81%) Enterobacter spp. four (7.27%). Antibiotic sensitivity of all bacteria done according to gram character HIV patients are already immuno compramised and treatment with antibiotics may further lower it. So we tried herbal, turmeric extract extracted by crude method, in different solvent to obtain its sensitivity pattern so it can be used to replace antibiotics.